Drug-Induced Liver Injury From Enobosarm (Ostarine), a Selective Androgen Receptor Modulator

Drug-Induced Liver Injury From Enobosarm (Ostarine), a Selective Androgen Receptor Modulator / Harjot Bedi, Carl Hammond, David Sanders, Hui-Min Yang, Eric M. Yoshida. - (ACG Case Reports Journal 8 (2021) 1 (January); p. 1-3)

  • PMID: 34368386
  • PMCID: PMC8337042
  • DOI: 10.14309/crj.0000000000000518


Abstract

Anabolic steroids are well-known to cause liver injury, which may manifest with jaundice and elevated liver enzymes. Selective androgen receptor modulators (SARMs) have been developed to enhance muscle bulk without the side effects associated with exogenous androgen steroids. We report a case of significant cholestatic liver injury associated with a SARM, ostarine (enobosarm), similar to that associated with anabolic steroids. Liver injury from SARMs has not been reported frequently, and we speculate that this may be seen more often as the consumption of SARMs increases in the athletic market.

Original document

Parameters

Science
Case report
Date
4 September 2021
People
Bedi, Harjot
Hammond, Carl
Sanders, David
Yang, Hui-Min
Yoshida, Eric M.
Country
Canada
Language
English
Other organisations
University of British Columbia (UBC)
Doping classes
S1. Anabolic Agents
Substances
Enobosarm (ostarine)
Selective androgen receptor modulators (SARMs)
Medical terms
Health / performance effects
Kidney / liver disease
Document category
Scientific article
Document type
Pdf file
Date generated
18 October 2021
Date of last modification
1 December 2021
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  • Legal Source
  • Education
  • Science
  • Statistics
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  • Country
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  • ADRV
  • Legal Terms
  • Sport/IFs
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  • Laboratories
  • Analytical aspects
  • Doping classes
  • Substances
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  • Various
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